Speaker Abstracts Poster Abstracts

One of the fundamental problems in neuroscience today is to understand how the activation of large populations of neurons give rise to the higher order functions of the brain including learning, memory, cognition, perception, action and ultimately conscious awareness. Electrophysiological recordings in behaving animals over the past forty years have revealed considerable information about what the firing patterns of single neurons encode in isolation, but it remains largely a mystery how collections of neurons interact to perform these functions. Recent technological advances have for the first time provided a glimpse into the global functioning of the brain. These technologies include functional magnetic resonance imaging, optical imaging methods including intrinsic, voltage-sensitive dye, and two-photon imaging, high-density electroencephalography and magnetoencephalography, and multi-microelectrode array electrophysiology. These technologies have expanded our knowledge of brain functioning beyond the single neuron level. At the same time, our understanding of how neuronal ensembles carry information has allowed the development of brain-machine interfaces (BMI) to enhance the capabilities of patients with sensory and motor deficits. Knowledge of how neuronal ensembles encode sensory stimuli has made it possible to develop perceptual BMIs for the hearing and visually impaired. Likewise, research in how neuronal ensembles decode motor intentions has resulted in motor BMIs by which people with severe motor disabilities can control external devices. There are three major goals of this conference. First and foremost, this conference is intended to bring scientific leaders from around the world to present their recent findings on the functioning of neuronal ensembles. A secondary goal of the conference is to provide an informal yet spectacular setting on Santorini in which conference attendees can discuss and share ideas outside of the presentations at the conference center. Third, this conference is the kick-off event for our long term project to form a systems neuroscience research institute within Greece. This institute will conduct state-of-the-art research, offer meetings and courses, and provide a center for visiting scientists from around the world to interact with Greek researchers and students.